Wish i knew this sooner... I noticed my drop rates fall into the dirt and decided to google it. Figured I would share.
Anti-farm code is the part of Guild Wars software used to reduce the benefits of repeatedly farming a single location, quest, or other objective. ANet has published few details about how it works; what little players know is based on limited experimentation and speculation.
Official facts
Since the first implementation:
Farming alone will yield fewer total items than farming with a full party, though more items per individual character.
Certain items are not affected:
Skill tomes
Scrolls
Dye
Rare materials
All rare (gold colored) items
All unique (green) items
Special event items
Repeated map entry does not reduce loot.